Insider Trading activities at Lexicon Pharmaceuticals, Inc. (LXRX)

Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Lexicon Pharmaceuticals, Inc. (LXRX) since 2015 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Lexicon Pharmaceuticals, Inc.. Table 2 shows the detailed insider transactions. This company's CIK number is 1062822.

Total stock buying since 2015: $223,469,563.
Total stock sales since 2015: $388,016.
Total stock option exercises since 2015: $187,945.


27 insiders reported insider trading activities at Lexicon Pharmaceuticals, Inc. (LXRX):
Insider trading activities of Mcdermott Wendy
Insider trading activities of Palantoni Frank
Insider trading activities of Invus Advisors, L.l.c.
Insider trading activities of Main Alan J
Insider trading activities of Tyle Praveen
Insider trading activities of Seth Kiernan
Insider trading activities of Defrancesco Lisa
Insider trading activities of Amouyal Philippe
Insider trading activities of Lefkowitz Robert J Md
Insider trading activities of Swain Judith L
Insider trading activities of Lapuerta Pablo
Insider trading activities of Nies Alan S
Insider trading activities of Invus Public Equities Advisors, Llc
Insider trading activities of Santini Alexander A
Insider trading activities of Sullivan Diane E.
Insider trading activities of Crum Brian T
Insider trading activities of Alexander Kristen
Insider trading activities of Tessmer James F
Insider trading activities of Kassler-taub Kenneth B.
Insider trading activities of Coats Lonnel
Insider trading activities of Sobecki Christopher J
Insider trading activities of Wade Jeffrey L
Insider trading activities of Stichting Administratiekantoor Westend
Insider trading activities of Debbane Raymond
Insider trading activities of Barker Sam L
Insider trading activities of Northcott John
Insider trading activities of Granowitz Craig B

Table 1. Yearly summary of insider stock purchases, sales, and option exercises at Lexicon Pharmaceuticals, Inc. (LXRX).
Insider Buying Insider Sales Option Exercises
Year Shares Value Shares Value Shares Value
2026 1,538,462 $2,000,000 0 $0 0 $0
2025 0 $0 0 $0 738,177 $0
2024 0 $0 0 $0 57,657,998 $0
2023 28,893,050 $73,567,062 0 $0 638,024 $0
2022 19,121,600 $47,804,000 0 $0 470,054 $0
2021 0 $0 22,912 $158,436 528,378 $39,720
2020 21,875,000 $70,000,000 0 $0 358,442 $0
2019 800,737 $1,932,636 0 $0 147,190 $0
2018 1,713,234 $20,277,481 10,000 $129,080 94,621 $101,500
2017 799,673 $7,888,384 0 $0 72,666 $0
2016 0 $0 7,500 $100,500 62,647 $46,725
2015 0 $0 0 $0 235,875 $0

Table 2. Monthly summary of insider trading at Lexicon Pharmaceuticals, Inc. (LXRX).
Trading Period Insider Buying Insider Sales Option Exercises
year-month Shares Value Shares Value Shares Value
2026-02 1,538,462 $2,000,000 0 $0 0 $0
2025-05 0 $0 0 $0 220,860 $0
2025-02 0 $0 0 $0 517,317 $0
2024-05 0 $0 0 $0 57,546,100 $0
2024-04 0 $0 0 $0 48,192 $0
2024-02 0 $0 0 $0 63,706 $0
2023-11 10,000 $10,100 0 $0 0 $0
2023-10 1,000,000 $1,103,993 0 $0 0 $0
2023-09 10,000 $13,799 0 $0 0 $0
2023-08 6,000 $11,040 0 $0 0 $0
2023-06 27,867,050 $72,428,130 0 $0 0 $0
2023-05 0 $0 0 $0 74,416 $0
2023-02 0 $0 0 $0 563,608 $0
2022-08 19,121,600 $47,804,000 0 $0 0 $0
2022-04 0 $0 0 $0 32,192 $0
2022-02 0 $0 0 $0 437,862 $0
2021-04 0 $0 0 $0 63,828 $0
2021-03 0 $0 22,912 $158,436 12,000 $39,720
2021-02 0 $0 0 $0 452,550 $0
2020-12 21,875,000 $70,000,000 0 $0 0 $0
2020-04 0 $0 0 $0 27,728 $0
2020-02 0 $0 0 $0 330,714 $0
2019-09 726,737 $1,839,226 0 $0 0 $0
2019-08 74,000 $93,410 0 $0 0 $0

Table 3. Detailed insider trading at Lexicon Pharmaceuticals, Inc. (LXRX)
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2026-02-02 Stichting Administratiekantoor Westend Buy 1,538,462 1.30 2,000,000
2025-05-13 Sullivan Diane E. (Director) Option Ex 36,810 .00 0
2025-05-13 Swain Judith L (Director) Option Ex 36,810 .00 0
2025-05-13 Amouyal Philippe (Director) Option Ex 36,810 .00 0
2025-05-13 Barker Sam L (Director) Option Ex 36,810 .00 0
2025-05-13 Sobecki Christopher J (Director) Option Ex 36,810 .00 0
2025-05-13 Debbane Raymond (Director) Option Ex 36,810 .00 0
2025-02-28 Mcdermott Wendy (SVP, Human Resources) Option Ex 98,956 .00 0
2025-02-28 Granowitz Craig B (SVP, Chief Medical Officer) Option Ex 137,934 .00 0
2025-02-28 Defrancesco Lisa (SVP, IR and Corp Comm) Option Ex 24,673 .00 0
2025-02-28 Crum Brian T (SVP, General Counsel & Secr.) Option Ex 128,940 .00 0
2025-02-28 Main Alan J (EVP, Innov & Chem Sciences) Option Ex 126,814 .00 0
2024-05-10 Invus Advisors, L.l.c. Option Ex 57,546,100 .00 0
2024-04-28 Swain Judith L (Director) Option Ex 8,032 .00 0
2024-04-28 Amouyal Philippe (Director) Option Ex 8,032 .00 0
2024-04-28 Barker Sam L (Director) Option Ex 8,032 .00 0
2024-04-28 Lefkowitz Robert J Md (Director) Option Ex 8,032 .00 0
2024-04-28 Sobecki Christopher J (Director) Option Ex 8,032 .00 0
2024-04-28 Debbane Raymond (Director) Option Ex 8,032 .00 0
2024-02-28 Granowitz Craig B (SVP, Chief Medical Officer) Option Ex 63,706 .00 0
2023-11-10 Coats Lonnel (Chief Executive Officer) Buy 10,000 1.01 10,100
2023-10-12 Debbane Raymond (Director) Buy 148,820 1.03 153,879
2023-10-11 Debbane Raymond (Director) Buy 342,874 1.08 370,646
2023-10-10 Debbane Raymond (Director) Buy 508,306 1.14 579,468
2023-09-14 Wade Jeffrey L (President and CFO) Buy 10,000 1.38 13,799
2023-08-04 Mcdermott Wendy (VP, Human Resources) Buy 6,000 1.84 11,040
2023-06-29 Coats Lonnel (Chief Executive Officer) Buy 10,000 2.16 21,600
2023-06-26 Coats Lonnel (Chief Executive Officer) Buy 10,000 2.18 21,790
2023-06-23 Mcdermott Wendy (VP, Human Resources) Buy 10,000 2.43 24,300
2023-06-23 Coats Lonnel (Chief Executive Officer) Buy 10,000 2.50 24,950
2023-06-22 Coats Lonnel (Chief Executive Officer) Buy 40,000 2.31 92,400
2023-06-20 Wade Jeffrey L (President and CFO) Buy 12,000 2.33 27,960
2023-06-05 Invus Advisors, L.l.c. (Director) Buy 27,775,050 2.60 72,215,130
2023-05-21 Swain Judith L (Director) Option Ex 9,302 .00 0
2023-05-21 Amouyal Philippe (Director) Option Ex 9,302 .00 0
2023-05-21 Palantoni Frank (Director) Option Ex 9,302 .00 0
2023-05-21 Nies Alan S (Director) Option Ex 9,302 .00 0
2023-05-21 Barker Sam L (Director) Option Ex 9,302 .00 0
2023-05-21 Lefkowitz Robert J Md (Director) Option Ex 9,302 .00 0
2023-05-21 Sobecki Christopher J (Director) Option Ex 9,302 .00 0
2023-05-21 Debbane Raymond (Director) Option Ex 9,302 .00 0
2023-02-28 Mcdermott Wendy (VP, Human Resources) Option Ex 18,943 .00 0
2023-02-28 Seth Kiernan (VP, Chief Commercial Officer) Option Ex 43,082 .00 0
2023-02-28 Kassler-taub Kenneth B. (SVP, Regulatory & QA) Option Ex 52,886 .00 0
2023-02-28 Alexander Kristen (VP, Finance and Accounting) Option Ex 18,717 .00 0
2023-02-28 Granowitz Craig B (SVP, Chief Medical Officer) Option Ex 27,917 .00 0
2023-02-28 Crum Brian T (SVP, General Counsel & Secr.) Option Ex 55,877 .00 0
2023-02-28 Coats Lonnel (Chief Executive Officer) Option Ex 209,327 .00 0
2023-02-28 Main Alan J (EVP, Innov & Chem Sciences) Option Ex 57,943 .00 0
2023-02-28 Wade Jeffrey L (President and CFO) Option Ex 78,916 .00 0
2022-08-01 Invus Advisors, L.l.c. (Director) Buy 16,173,800 2.50 40,434,500
2022-08-01 Debbane Raymond (Director) Buy 1,965,200 2.50 4,913,000
2022-04-30 Swain Judith L (Director) Option Ex 4,024 .00 0
2022-04-30 Amouyal Philippe (Director) Option Ex 4,024 .00 0
2022-04-30 Palantoni Frank (Director) Option Ex 4,024 .00 0
2022-04-30 Nies Alan S (Director) Option Ex 4,024 .00 0
2022-04-30 Barker Sam L (Director) Option Ex 4,024 .00 0
2022-04-30 Lefkowitz Robert J Md (Director) Option Ex 4,024 .00 0
2022-04-30 Sobecki Christopher J (Director) Option Ex 4,024 .00 0
2022-04-30 Debbane Raymond (Director) Option Ex 4,024 .00 0
2022-02-28 Seth Kiernan (VP, Chief Commercial Officer) Option Ex 30,128 .00 0
2022-02-28 Kassler-taub Kenneth B. (SVP, Regulatory & QA) Option Ex 36,628 .00 0
2022-02-28 Alexander Kristen (VP, Finance and Accounting) Option Ex 11,300 .00 0
2022-02-28 Crum Brian T (SVP, General Counsel & Secr.) Option Ex 40,880 .00 0
2022-02-28 Coats Lonnel (Chief Executive Officer) Option Ex 197,343 .00 0
2022-02-28 Main Alan J (EVP, Innov & Chem Sciences) Option Ex 54,650 .00 0
2022-02-28 Wade Jeffrey L (President and CFO) Option Ex 66,933 .00 0
2021-04-24 Swain Judith L (Director) Option Ex 10,638 .00 0
2021-04-24 Palantoni Frank (Director) Option Ex 10,638 .00 0
2021-04-24 Nies Alan S (Director) Option Ex 10,638 .00 0
2021-04-24 Lefkowitz Robert J Md (Director) Option Ex 10,638 .00 0
2021-04-24 Sobecki Christopher J (Director) Option Ex 10,638 .00 0
2021-04-24 Debbane Raymond (Director) Option Ex 10,638 .00 0
2021-03-15 Tessmer James F (VP, Finance & Accounting) Sale 22,912 6.92 158,436
2021-03-15 Tessmer James F (VP, Finance & Accounting) Option Ex 12,000 3.31 39,720
2021-02-28 Crum Brian T (VP, General Counsel & Secr.) Option Ex 38,765 .00 0
2021-02-28 Coats Lonnel (President and CEO) Option Ex 192,885 .00 0
2021-02-28 Tessmer James F (VP, Finance & Accounting) Option Ex 28,316 .00 0
2021-02-28 Tyle Praveen (EVP, R&D) Option Ex 68,007 .00 0
2021-02-28 Main Alan J (EVP, Innov & Chem Sciences) Option Ex 56,468 .00 0
2021-02-28 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 68,109 .00 0
2020-12-16 Stichting Administratiekantoor Westend (Director) Buy 10,937,500 3.20 35,000,000
2020-12-16 Invus Advisors, L.l.c. (Director) Buy 10,937,500 3.20 35,000,000
2020-04-26 Swain Judith L (Director) Option Ex 3,466 .00 0
2020-04-26 Amouyal Philippe (Director) Option Ex 3,466 .00 0
2020-04-26 Palantoni Frank (Director) Option Ex 3,466 .00 0
2020-04-26 Nies Alan S (Director) Option Ex 3,466 .00 0
2020-04-26 Barker Sam L (Director) Option Ex 3,466 .00 0
2020-04-26 Lefkowitz Robert J Md (Director) Option Ex 3,466 .00 0
2020-04-26 Sobecki Christopher J (Director) Option Ex 3,466 .00 0
2020-04-26 Debbane Raymond (Director) Option Ex 3,466 .00 0
2020-02-28 Crum Brian T (VP, General Counsel & Secr.) Option Ex 20,252 .00 0
2020-02-28 Santini Alexander A (EVP and CCO) Option Ex 36,263 .00 0
2020-02-28 Coats Lonnel (President and CEO) Option Ex 116,647 .00 0
2020-02-28 Lapuerta Pablo (EVP and CMO) Option Ex 38,846 .00 0
2020-02-28 Tyle Praveen (EVP, R&D) Option Ex 39,316 .00 0
2020-02-28 Main Alan J (EVP, Commercial Supply Ops) Option Ex 37,252 .00 0
2020-02-28 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 42,138 .00 0
2019-09-18 Santini Alexander A (EVP and CCO) Buy 4,500 3.38 15,187
2019-09-18 Coats Lonnel (President and CEO) Buy 50,000 3.10 155,000
2019-09-17 Coats Lonnel (President and CEO) Buy 50,000 3.12 156,250
2019-09-16 Sobecki Christopher J (Director) Buy 25,000 2.52 63,049
2019-09-16 Debbane Raymond (Director) Buy 93,773 2.70 253,374
2019-09-13 Sobecki Christopher J (Director) Buy 99,249 2.38 236,708
2019-09-13 Debbane Raymond (Director) Buy 206,742 2.42 491,253
2019-08-19 Coats Lonnel (President and CEO) Buy 3,000 1.40 4,194
2019-08-16 Coats Lonnel (President and CEO) Buy 37,000 1.34 49,617
2019-08-02 Tessmer James F (VP, Finance & Accounting) Buy 10,000 1.14 11,399
2019-08-02 Barker Sam L (Director) Buy 24,000 1.18 28,200
2019-02-28 Santini Alexander A (EVP and CCO) Option Ex 13,408 .00 0
2019-02-28 Coats Lonnel (President and CEO) Option Ex 48,101 .00 0
2019-02-28 Lapuerta Pablo (EVP and CMO) Option Ex 19,932 .00 0
2019-02-28 Tessmer James F (VP, Finance & Accounting) Option Ex 10,226 .00 0
2019-02-28 Tyle Praveen (EVP, R&D) Option Ex 12,717 .00 0
2019-02-28 Main Alan J (EVP, Commercial Supply Ops) Option Ex 20,151 .00 0
2019-02-28 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 22,655 .00 0
2018-06-28 Invus Public Equities Advisors, Llc (Director) Buy 57,724 12.46 718,952
2018-06-27 Invus Public Equities Advisors, Llc (Director) Buy 125,114 12.54 1,568,429
2018-06-21 Invus Public Equities Advisors, Llc (Director) Buy 51,600 13.27 684,628
2018-06-20 Invus Public Equities Advisors, Llc (Director) Buy 12,391 13.29 164,614
2018-06-19 Invus Public Equities Advisors, Llc (Director) Buy 8,982 13.45 120,816
2018-06-18 Invus Public Equities Advisors, Llc (Director) Buy 36,584 13.06 477,933
2018-06-14 Invus Public Equities Advisors, Llc (Director) Buy 9,200 12.66 116,462
2018-06-12 Invus Public Equities Advisors, Llc (Director) Buy 107,023 12.83 1,373,212
2018-06-11 Invus Public Equities Advisors, Llc (Director) Buy 98,626 12.75 1,257,481
2018-06-08 Tessmer James F (VP, Finance & Accounting) Sale 10,000 12.91 129,080
2018-06-08 Tessmer James F (VP, Finance & Accounting) Option Ex 10,000 10.15 101,500
2018-06-08 Invus Public Equities Advisors, Llc (Director) Buy 29,747 12.89 383,438
2018-06-07 Invus Public Equities Advisors, Llc (Director) Buy 57,439 12.93 742,513
2018-06-06 Invus Public Equities Advisors, Llc (Director) Buy 95,079 12.58 1,196,379
2018-06-05 Invus Public Equities Advisors, Llc (Director) Buy 173,121 12.46 2,156,222
2018-06-04 Invus Public Equities Advisors, Llc (Director) Buy 121,803 12.24 1,490,625
2018-06-01 Invus Public Equities Advisors, Llc (Director) Buy 147,339 12.22 1,800,040
2018-05-31 Invus Public Equities Advisors, Llc (Director) Buy 147,339 11.62 1,712,079
2018-05-30 Invus Public Equities Advisors, Llc (Director) Buy 147,339 10.32 1,520,980
2018-05-29 Invus Public Equities Advisors, Llc (Director) Buy 147,339 9.84 1,450,405
2018-05-25 Invus Public Equities Advisors, Llc (Director) Buy 138,700 9.62 1,334,987
2018-05-23 Santini Alexander A (EVP and CCO) Buy 745 9.78 7,286
2018-02-28 Santini Alexander A (EVP and CCO) Option Ex 4,945 .00 0
2018-02-28 Coats Lonnel (President and CEO) Option Ex 24,588 .00 0
2018-02-28 Lapuerta Pablo (EVP and CMO) Option Ex 14,184 .00 0
2018-02-28 Tessmer James F (VP, Finance & Accounting) Option Ex 7,353 .00 0
2018-02-28 Tyle Praveen (EVP, R&D) Option Ex 2,990 .00 0
2018-02-28 Main Alan J (EVP, Commercial Supply Ops) Option Ex 14,533 .00 0
2018-02-28 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 16,028 .00 0
2017-11-17 Invus Public Equities Advisors, Llc (Director) Buy 50,000 9.85 492,500
2017-11-15 Coats Lonnel (President and CEO) Buy 10,000 9.91 99,100
2017-11-15 Invus Public Equities Advisors, Llc (Director) Buy 130,727 10.21 1,334,461
2017-11-14 Invus Public Equities Advisors, Llc (Director) Buy 215,133 9.47 2,037,954
2017-11-14 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Buy 2,000 9.48 18,962
2017-11-13 Invus Public Equities Advisors, Llc (Director) Buy 215,133 9.75 2,097,977
2017-11-10 Invus Public Equities Advisors, Llc (Director) Buy 145,680 9.74 1,418,340
2017-09-15 Coats Lonnel (President and CEO) Buy 30,000 12.55 376,590
2017-09-15 Barker Sam L (Director) Buy 1,000 12.50 12,500
2017-02-28 Santini Alexander A (EVP and CCO) Option Ex 2,352 .00 0
2017-02-28 Coats Lonnel (President and CEO) Option Ex 19,226 .00 0
2017-02-28 Lapuerta Pablo (EVP and CMO) Option Ex 14,099 .00 0
2017-02-28 Tessmer James F (VP, Finance & Accounting) Option Ex 6,939 .00 0
2017-02-28 Main Alan J (EVP, CMC and Supply Operations) Option Ex 14,391 .00 0
2017-02-28 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 15,659 .00 0
2016-06-06 Tessmer James F (VP, Finance & Accounting) Sale 1,500 15.00 22,500
2016-06-06 Tessmer James F (VP, Finance & Accounting) Option Ex 1,500 6.23 9,345
2016-05-23 Tessmer James F (VP, Finance & Accounting) Sale 6,000 13.00 78,000
2016-05-23 Tessmer James F (VP, Finance & Accounting) Option Ex 6,000 6.23 37,380
2016-02-29 Coats Lonnel (President and CEO) Option Ex 10,835 .00 0
2016-02-29 Lapuerta Pablo (EVP and CMO) Option Ex 11,728 .00 0
2016-02-29 Tessmer James F (VP, Finance & Accounting) Option Ex 5,828 .00 0
2016-02-29 Main Alan J (EVP, CMC and Supply Operations) Option Ex 12,807 .00 0
2016-02-29 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 13,949 .00 0
2015-03-02 Northcott John (VP, Marketing, Comm Strategy) Option Ex 11,250 .00 0
2015-03-02 Lapuerta Pablo (EVP and CMO) Option Ex 50,250 .00 0
2015-03-02 Tessmer James F (VP, Finance & Accounting) Option Ex 29,625 .00 0
2015-03-02 Main Alan J (EVP, CMC and Supply Operations) Option Ex 69,000 .00 0
2015-03-02 Wade Jeffrey L (EVP, Corp Adm Affairs and CFO) Option Ex 75,750 .00 0

Insider trading activities including stock purchases, stock sales, and option exercises of LXRX listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Lexicon Pharmaceuticals, Inc. (symbol LXRX, CIK number 1062822) see the Securities and Exchange Commission (SEC) website.



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